Colleen Van Deusen was a teacher at Lake View High School. She and Principal McCullough take their students Rennie Wickham, Sean Robertson, Julius Gaw, Tamara Mason, Eva Watanabe (Kelly Hu), Wayne Webber, Miles Wolfe and J.J. on the S.S. Lazarus for a cruise to New York City, unaware that Jason has stowed away on the ship.
Jason murders the students in cold blood one by one, while Van Deusen survives the massacre on the boat. Later, Colleen, along with Rennie, Sean, McCullough, Julius, and Toby get on a lifeboat and abandoned The Lazarus. Jason, unknown to the lifeboat passengers, has come along for the ride.
While the group is on patrol, the cop is killed by Jason and Rennie takes the car to escape. After being surprised by Jason, Rennie crashed the car into a wall killing Colleen instantly.
- She is the second character in the film who dies accidentally, the first is a crew member on the S.S. Lazarus.